Dr Alessandro Siani
Biography
I obtained my BSc in General and Applied Biology from the University of Naples “Federico II” (Italy) in 2006. My BSc research project aimed to elucidate the impact of epigenetic factors (specifically, H3K4 methylation) on the development of oral carcinoma. Research into the molecular aetiology of human pathology was also the main focus of my MSc project, carried out at the Telethon Institute of Genetics and Medicine (TIGEM, Naples, Italy). During my time at TIGEM I investigated the molecular and cellular basis of the neurobehavioural phenotype observed in mouse models of 22q11 deletion syndrome (also known as velocardiofacial or DiGeorge syndrome). I moved to the UK in 2010 for my PhD, which was carried out at the Laboratory of Polymers and Biomaterials of the University of Manchester. My PhD research project focused on understanding the mechanical and biochemical factors underpinning the myofibroblast differentiation process, key cellular event leading to fibrotic degeneration in a number of pathological conditions. During my PhD and post-doc, also at the University of Manchester, I became increasingly engaged in my department’s didactic and outreach activities. As a result, I decided to further pursue my dedication to scientific teaching and communication by enrolling in a secondary (11-18) science PGCE, which I was awarded in 2016 from the University of Manchester.
Research outputs
2024
Susceptibility to scientific misinformation and perception of news source reliability in secondary school students
Dacin, C., Joseph, M., Siani, A.
9 Jul 2024, In: Discover Education. 3, 12p., 93
Mixed messages, broken trust, avoidable deaths: a critical appraisal of the UK government’s response to the COVID-19 pandemic
Siani, A.
17 Jan 2024, In: Open Health. 5, 7p., 20230016
2023
Polysulfide nanoparticles inhibit fibroblast-to-myofibroblast transition via extracellular ROS scavenging and have potential anti-fibrotic properties
Donno, R., D’Arcy, R., El Mohtadi, F., Roberts, I. V., Siani, A., Teixeira, L. I., Tirelli, N.
1 Oct 2023, In: Biomaterials Advances. 153, 13p., 213537
Self-confidence and STEM career propensity: lessons from an all-girls secondary school
Harris, J., Siani, A.
23 Mar 2023, In: Open Education Studies. 5, 1, 10p., 20220180
Scientific misinformation and mistrust of COVID-19 preventive measures among the UK population: a pilot study
Green, I., Siani, A.
30 Jan 2023, In: Vaccines. 11, 2, 10p., 301
COVID: unvaccinated people may be seen as ‘free riders’ and face discrimination
Siani, A.
6 Jan 2023, In: The Conversation