Sequencing and Bioinformatics Group laboratory

Our Sequencing and Bioinformatics laboratory is the hub for working with a variety of DNA and RNA sequencing tools, as well as high-throughput nanopore sequencers.

Through hands-on experiments, you'll see how DNA and RNA pass through tiny pores and are then decoded into their constituent parts by machine learning algorithms.

The facility includes a wide range of computational tools to analyse nanopore sequencing data and other next-generation sequencing platforms. Additionally, we maintain pipelines for sequencing applications such as whole (meta) genome assemblies, RNA sequences, targeted sequences, and amplicon sequences.

Our lab collaborates on a wide range of research projects, especially those that use Illumina and Oxford Nanopore Technologies (ONT) for high-throughput sequencing, and has recently served as a virus sequencing site for the COVID-19 Genomics UK (COG-UK) Consortium. We also host a range of research projects within the Centre for Enzyme Innovation (CEI), exploring the genomes of naturally occurring microorganisms to identifying enzymes with potential industrial applications.